Symptomatic: The Symptom-Based Handbook for Ehlers-Danlos Syndromes and Hypermobility Spectrum Disorders

Symptomatic: The Symptom-Based Handbook for Ehlers-Danlos Syndromes and Hypermobility Spectrum Disorders offers a novel approach structured around the panoply of 75 symptoms with which a person with Ehlers-Danlos syndromes (EDS) and hypermobility spectrum disorders (HSD) may present to a clinician. The content is arranged intuitively from head to feet, with each chapter integrating clinical case studies with a concise discussion and two important diagnostic tools: a simplified algorithm for diagnosing and treating each symptom and differential diagnoses and alternative explanations for their symptoms. This is a handbook that combines the expertise of some 70 leading clinicians, representing more than 30 specialties.

This book is suited for clinicians who need a concise and straight-forward presentation of the various and complex symptoms they confront in their clinical practice. It brings forth a field of knowledge emerging from interdisciplinary collaboration despite the pressures of specialization that bridges gaps in understanding between the several dozen disciplines implicated in EDS and HSD.

A collective resource on how to diagnose and treat the complex symptoms of EDS and HSD

Symptomatic: The Symptom-Based Handbook for Ehlers-Danlos Syndromes and Hypermobility Spectrum Disorders offers a novel approach structured around the panoply of 75 symptoms with which a person with Ehlers-Danlos syndromes (EDS) and hypermobility spectrum disorders (HSD) may present to a clinician. The content is arranged intuitively from head to feet, with each chapter integrating clinical case studies with a concise discussion and two important diagnostic tools: a simplified algorithm for diagnosing and treating each symptom and differential diagnoses and alternative explanations for their symptoms. This is a handbook that combines the expertise of some 70 leading clinicians, representing more than 30 specialties.

This book is suited for clinicians who need a concise and straight-forward presentation of the various and complex symptoms they confront in their clinical practice. It brings forth a field of knowledge emerging from interdisciplinary collaboration despite the pressures of specialization that bridges gaps in understanding between the several dozen disciplines implicated in EDS and HSD.

ClairFrancomano received her M.D. from Johns Hopkins University School of Medicine and completed her training in Internal Medicine and Medical Genetics at Johns Hopkins. She served on the full-time faculty at Johns Hopkins and in the Intramural Research Program of the NIH, and subsequently,Greater Baltimore Medical Center as Director of Adult Genetics at the Harvey Institute of Human Genetics. In 2019, she became Professor of Medical and Molecular Genetics at the Indiana University School of Medicine and Director of the Residency Training Program in Clinical Genetics. Dr. Francomano has been involved in the care of patients with Ehlers-Danlos syndrome throughout her career. She serves on the Steering Committee for the International Consortium on the Ehlers-Danlos Syndromes and Related Conditions, and has chaired the Consortium’s Committee on Classical Ehlers-Danlos Syndrome since 2016.

Alan Hakim MA, FRCP received his degrees in medicine from Cambridge University and Addenbrookes Hospital, and completed his Medical training at Addenbrookes in Cambridge and then University College London Hospitals. He received his consultant certification and Fellowship from the Royal College of Physicians in 2000 and 2005, respectively. Having held many clinical leadership roles and practiced at Thomas’ Hospital, London, Whipps Cross Hospital and Barts Health NHS Trust, he currently practices as an Acute Physician, Rheumatologist, and specialist of heritable connective tissue disorders, authoring five medical books. He is Chief Operating Officer of the Ehlers-Danlos Society, and Steering Committee member of The International Consortium on the Ehlers-Danlos Syndromes and Hypermobility Spectrum Disorders.

Lansdale Henderson graduated with Honors in neuroscience as an Echols Scholar and Lawn Resident from the University of Virginia. He studied adult neurogenesis in laboratories at the University of Virginia Medical School, the National Institutes of Health, and the Pasteur Institute, publishing in the Journal of Neuroscience and teaching an undergraduate course. He progressed to health and science policy as a fellow for two U.S. Senators. While subsequently staffing the Maryland Senate President, he studied the “Great Books” at St. Johns College, earning Honors for his graduate thesis in political theory. As the 2018 Longvue Fellow, he earned a second master’s degree from the Johns Hopkins School of Advanced International Studies (SAIS). He has since co-founded Airbase Breathing Company, LLC to develop a COVID-19 therapeutic, while holding a research position with the Metropolitan Neurosurgery Group. Drawing on his multidisciplinary background and his longstanding familiarity with EDS patients and research, he is honored to further this important and highly interdisciplinary endeavor

Lansdale Henderson MD graduated with Honors in neuroscience as an Echols Scholar and Lawn Resident from the University of Virginia. He studied adult neurogenesis in laboratories at the University of Virginia Medical School, the National Institutes of Health, and the Pasteur Institute, publishing in the Journal of Neuroscience and teaching an undergraduate course. He progressed to health and science policy as a fellow for two U.S. Senators. While subsequently staffing the Maryland Senate President, he studied the “Great Books” at St. Johns College, earning Honors for his graduate thesis in political theory. As the 2018 Longvue Fellow, he earned a second master’s degree from the Johns Hopkins School of Advanced International Studies (SAIS). He has since co-founded Airbase Breathing Company, LLC to develop a COVID-19 therapeutic, while holding a research position with the Metropolitan Neurosurgery Group. Drawing on his multidisciplinary background and his longstanding familiarity with EDS patients and research, he is honored to further this important and highly interdisciplinary endeavor