The Exposome: A New Paradigm for the Environment and Health

"In chapter 5, Dean Miller provides a comparison of "-omes and citations" from 2013 to 2019. Given the genealogy of the genome (first noted in 1920), the proteome (1994), the transcriptome (1997), epigenomics (1950s), toxigenomics (1999), and the exposome (2005), the latter is certainly the newcomer, making its 10,000-fold citation expansion (2005-2015) astonishing. Exposome-related research and applications are not only relevant to environmental health sciences but factors that will define environmental health sciences and likely public health as well." --Doody

The Exposome: A New Paradigm for the Environment and Health, Second Edition, is a thoroughly expanded and updated edition of The Exposome: A Primer, the first book dedicated to the topic. This new release outlines the purpose and scope of this emerging field of study, its practical applications, and how it complements a broad range of disciplines. The book contains sections on -omics-based technologies, newer detection methods, managing and integrating exposome data (including maps, models, computation and systems biology), and more. Both students and scientists in toxicology, environmental health, epidemiology and public health will benefit from this rigorous, yet readable, overview.

This updated edition includes a more in-depth examination of the exposome, including full references, further reading and thought questions.

Updates on the emerging field of study of the exposome, its applications and how it complements a range of disciplines

Gary W. Miller, PhD is the Vice Dean for Research Strategy and Innovation and Professor of Environmental Health Sciences at the Mailman School of Public Health at Columbia University. He was founding director of the HERCULES Exposome Research Center at Emory University, the first exposome-based center in the U.S. In addition to his work on the exposome, his research interests include the role of environmental factors in neurodegenerative disorders, such as Parkinson’s disease and Alzheimer’s disease, and the regulation of dopamine signaling in the brain. He served as Editor-in-Chief of Toxicological Sciences, the official journal of the Society of Toxicology, from 2013-2019.