THE MOST ADVANCED COLLAGEN SUPPLEMENT This is one of the ultimate skin care products on the market. It contains 100% Premium-GradeActuMarine Collagen, a low molecular weight fish collagen peptide that was developed in Japan. It is now being recognized as the gold standard in collagen because it is tastless, odorless and highly absorbable. Your skin will be thanking you from the very first sip!
Collagen, the “structural skin super-protein”, is a hot topic of research in aesthetic dermatology due to its central role in anti-aging and skin repair. Collagen is composed of the amino acids Glycine, Proline, Arginine, and Hydroxyproline which are incorporated into collagen fibrils by fibroblasts in the skin, connective tissue and other organs. These fibrils bind to form long fibers with enormous tensile strength which provide structural support to everything from our hair and skin to our bones and internal organs.Collagen is the primary source of rigidity in soft tissues.
All Collagens are the Same, Right?
Anyone shopping in stores or online for skin care has likely seen dozens or even hundreds of collagen products promising incredible skin benefits. While decades of research on collagen supplementation back up these claims, do they all really work? The truth is, the quality and function of collagen varies greatly depending on the molecular profile of the collagen. New studies show that for human health, collagen supplements should contain high levels of the hydroxyproline (HYP) peptide. Relumins ActuMarine Collagen is derived from fish scales and skin, the best source for HYP collagen. Clinicians, estheticians, and practitioners choose this type of collagen over any other because their clients expect to see results quickly. With Relumins Premium Collagen Blend, results can be seen as quickly as 8 hours.
So, why aren’t all Collagen Supplements made this way?
The cost of high quality fish collagen can cost manufacturers up to 25 times more than cheaper animal collagens like Bovine and Porcine. The technology used to extract, purify and hydrolyze fish collagen is also significantly more sophisticated. Relumins sought out the most cutting edge producers of marine collagen and discovered a patented process only available in Japan to create their ActuMarine Collagen.
But I’m Under 40, do I Still Need Collagen?
Collagen peaks when you’re still in the womb. Even in our 20s, our skin still experiences the same damaging stressors as when we are older. For lifelong healthy skin, hair and nails, it’s never too early to add a high quality collagen to your diet.
What is Collagen?
Collagen, the “structural skin super-protein”, is a hot topic of research in aesthetic dermatology due to its central role in anti-aging and skin repair. Collagen is composed of the amino acids Glycine, Proline, Arginine, and Hydroxyproline which are incorporated into collagen fibrils by fibroblasts in the skin, connective tissue and other organs. These fibrils bind to form long fibers with enormous tensile strength which provide structural support to everything from our hair and skin to our bones and internal organs. Collagen is the primary source of rigidity in soft tissues. Its long fibrous structure can flex and bend and return back to its original shape. This allows us to have smooth, strong skin and youthful, flexible joins. It is so essential to the structure of our bodies and organs that it’s no surprise collagen makes up 70% of skin protein and 30% of the body’s total protein!
Collagen Loss, Damage and Aging
Repair and production of collagen slow with age or from stresses and health conditions. These complex fibers are constantly taking damage and the body must keep up by synthesizing new collagen proteins to repair and rebuild them. Physical and chemical stressors such as skin wounds, burns or bone fractures lead to cascades that break apart the proteins into constituent peptides while chemical stressors such as oxidative stress reduce the body’s ability to regenerate. Stressors like acne and sunburn are common causes of repeated skin trauma. These stressors create inflammatory and oxidative stress within the cells. Collagen that is damaged by physical or chemical processes can be repaired, but the fibers will become thicker, inelastic and brittle. This weakened collagen doesn’t provide the same flexibility and strength and is more prone to breaking down. Loss of collagen leads to wrinkles, sagging and poor skin hydration along with stiff and achy joints. For youthful skin and joints, collagen needs to be maintained through supplementation, nutrition and protection.
Loss of collagen leads to wrinkles, sagging and poor skin hydration along with stiff and achy joints. For youthful skin and joints, collagen needs to be maintained through supplementation, nutrition and protection.
Relumins Collagen Blend contains a whole host of ingredients that improve collagen intake: Vitamin C, Green Tea Extract, Hyaluronic Acid, CoQ10, Glucosamine, L-Glutathione, Acai Berry Extract and Pearl Coix Extract.
Vitamin C is essential for the natural production of collagen. It directly activates the transcription of collagen synthesis and stabilizes procollagen mRNA3 . It also inhibits the expression of Matrix Metalloproteinases (MMPs)
The dramatic increase in skin collagen within 12 hours demonstrates collagen “rushing” to where it is needed.
Efficacy of Oral Collagen Supplementation
The effectiveness of collagen peptides, the smallest molecular units of collagen, as an oral supplement for skin support has been documented in numerous studies. A 2008 study from Tokyo University of Agriculture & Technology looked at oral ingestion of the peptide at a dosage of 0.2 grams of collagen per kilogram of body weight per day. They demonstrated that it was effective at reducing or mitigating UV-Binduced skin damage such as decreases in skin hydration, hyperplasia of the epidermis, and decreases in soluble type I collagen. A 2008 literature review from the Archives of Dermatological Research concluded, based on a number of clinical and preclinical studies, that oral ingestion of hydrolyzed collagen could achieve beneficial skin effects. Furthermore, Oesser, et. Al (1999) studied oral administration of 14C labeled collagen in mice. They observed 95% absorption of collagen peptides within 12 hours of oral ingestion. Collagen content within skin cells peaked 12 hours after ingestion and remained elevated for 96 hours. This is strong evidence that points to a mechanism allowing the collagen peptides to rush to where they are needed.
Actumarine Collagen: Why it’s Better
Relumins uses premium collagen derived from fish scales. The absorption properties of marine collagen differ from bovine or porcine collagens. In a 2007 Japanese clinical study, researchers found that oral ingestion of fish scale collagen lead to substantial increases of hydroxyproline (hyp) and hyp-peptides in plasma. This increase was significantly higher from fish scale collagen than from porcine collagen. Hydroxyproline is a major, essential component of collagen that permits the twisted, helical structure of the collagen proteins to remain structurally stable. The protein structure and content of fish collagen was also markedly different from other types of collagen. Ala-Hyp, Leu-Hyp, Ile-Hyp, Phe-Hyp, and ProHyp-Gly were detected only with fish scale or fish skin gelatin hydrolysates. AlaHyp-Gly and Ser-Hyp-Gly were detected only with fish scale gelatin hydrolysate. These Hyp containing peptides are the most important functional peptides in collagen formation and maintenance.
Supporting Collagen Maintenance and Synthesis with Natural Compounds
There are many other ways to protect and restore collagen. There are several natural supplements that demonstrate marked effects when added to the diet. Relumins Collagen Blend contains a whole host of these ingredients: Vitamin C, Green Tea Extract, Hyaluronic Acid, CoQ10, Glucosamine, L-Glutathione, Acai Berry Extract and Pearl Coix Extract. Vitamin C is essential for the natural production of collagen. It directly activates the transcription of collagen synthesis and stabilizes procollagen mRNA. It also inhibits the expression of Matrix Metalloproteinases (MMPs). Collagen is degraded by MMPs or other collagenase enzymes which are often released as a result of oxidative or inflammatory activity. CoQ10 inhibits UVA and UVB induced collagen degrading factors such as collagenase and MMP. Green Tea Extract has clinically demonstrated anticollagenase properties. In general, antioxidant effects are thought to inhibit the expression of collagen degrading compounds. Vitamin C, CoQ10, LGlutathione, Acai Berry Extract (Vitamin E), Green Tea Extract, Pearl Coix Extract (Vitamin B2)16 and Glucosamine are all potent antioxidants.
Glycosaminoglycan Support
Relumins Premium Collagen Blend contains Hyaluronic Acid, a glycosaminoglycan that is a major component of then skin support structure. Hyaluronic acid is both lubricating and shock absorbing with an incredible water holding capacity. This moisture retention keeps skin smooth and plump. Hyaluronic Acid decreases with age. And much like collagen, it can be orally supplemented. When clinically tested, oral ingestion of Hyaluronic Acid increased skin moisture content and smoothness and reduced wrinkles. An additional glycosaminoglycan benefit comes from the glucosamine found in the formula. A study done by the Journal of Clinical Dermatology found that Glucosamine promotes the production of glycosaminoglycans such as hyaluronic acid, accelerates wound healing, improves skin hydration, and decreases wrinkles.
Photoprotective Properties
UV radiation is known to be one of the most damaging stressors on skin. Exposure to too much sunlight causes an influx of MMPs and neutrophils containing proteolytic enzymes into the dermis. These enzymes destroy collagen and elastin and age skin10. CoQ105 , Vitamin C4 , and Vitamin E15 have all been demonstrated to counteract these effects. UV can also damage skin by increasing oxidative stress. Sun damage leads to the formation of peroxides and free radicals which can break apart DNA and rapidly age skin. Antioxidant ingredients will effectively reduce UV induced reactive oxygen species in the skin. The Glutathione, CoQ10, Vitamin C, Vitamin E and Green Tea Extract found in this formula are all potent antioxidants.
Antioxidants for Anti-Inflammation
Postinflammatory hyperpigmentation is a common issue faced by darker skinned individuals in which inflammatory injury can cause skin discoloration like dark spots or patches. Even acne or a sunburn can leave long lasting dark marks. Preventing inflammation from occurring in the first place can minimize discoloration from injuries. Relumins Premium Collagen Blend is loaded with antioxidant ingredients which help combat the damaging effects of inflammation.
Ultimate Drinkability
Relumins Collagen Blend is the best tasting collagen drink available today. This premium grade collagen is tasteless and odorless without the bad taste that comes with other collagen drinks. We mix our collagen with natural fruit juice to create a delicious vanilla, pineapple & blueberry flavor drink. Its low molecular weight and high purity cause it to rapidly dissolve in water. Just pour a sachet into a glass of water and enjoy!
Doctors First Choice Our scientists and product engineers have access to world-class data, research and pharmaceutical staff, putting them at the leading edge of natural skincare & lifelong beauty.
Relumins products are manufactured to the strictest QC standards, pharmaceutical-grade beauty and skincare products are manufactured to precise safety standards following best industry practices.
Relumins Labs is based in central New Jersey, the heart of the North American pharmaceutical industry.
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